Bekhterev's Disease (Ankylosing Spondylitis): Diagnosis & Treatment

Overview
Bekhterev’s disease, or ankylosing spondylitis, is a chronic rheumatic condition affecting the spinal joints, leading to inflammation of the ligamentous structures and the formation of ankylosis (fusion of the vertebrae). The sacroiliac joint and lumbar spine are most commonly affected, but as the disease progresses, other spinal regions may also be involved.

Diagnosis
Diagnostic methods include:

• Spinal X-ray – Detects structural changes and ankylosis

• Bone scintigraphy – Identifies areas of active inflammation

• CT and MRI – Provides detailed imaging of spinal and joint involvement

• Blood test for HLA-B27 antigen – Assesses genetic predisposition to the disease

Treatment
Management focuses on symptom relief, maintaining mobility, and preventing complications. Treatment options include:

• Posture correction and physical therapy – Exercises to maintain flexibility and reduce stiffness

• Medical treatment – Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, disease-modifying antirheumatic drugs (DMARDs), methotrexate, and corticosteroids

• Surgical treatment – Osteotomy (corrective surgery) or joint replacement in severe cases

Cost of Diagnosis & Treatment: 2,300,000 KRW + treatment